ZEB2 and Hirschsprung disease: The field also studied compound Zeb1;Zeb2 mutant mice for few sites in the embryo where their presence overlaps, i.e., in somitogenesis [56,57,58], as well as compound Zeb2+/− mutant mice with other mutant mice for Hirschsprung disease genes in order to study NCC-derived ENS cells [59,60].