ZEB2 and neoplasm: ZEB2 is further studied in tumor initiation in concert with other regulators of epithelial–mesenchymal transition (EMT) [40] and metastasis [41,42], collagen fibrillogenesis in the dermal component of the skin [43], tight junction formation in cells and epithelial barrier function of the epidermis [44], and in the kidney as novel primary glomerular cystic disease gene [45].