IFIT3 and acute promyelocytic leukemia: A receiver operating characteristic curve (ROC) analysis of RIG-G mRNA in peripheral blood of APL patients indicated that the cutoff value was 5.50 × 103 copies/μL, and the area under the curve (AUC) of RIG-G was 0.974, signifying RIG-G mRNA as a strong predictor of APL, with 83.33% sensitivity (17/20) and 100% specificity (20/20) (Figure 4D).