BRAF‐V600E‐induced autophagy in response to increased ER stress is often a cytoprotective process (Rather et al., 2020), and pharmacological inhibition of autophagy was shown to improve the potency of anti‐cancer drugs in melanoma harboring the BRAF‐V600E mutation (Goodall et al., 2014; Ma et al., 2014). The gene discussed is BRAF; the disease is cancer.