Thus, the present study presumes that, in addition to the CMV CP regulation of 2b (Zhang et al., 2017) and CMV 1a‐mediated regulation of the 2b–AGO1 association (Watt et al., 2020), the equilibrium between CMV‐2b and CsRDR1c protein levels controls virus accumulation and the infection progress. The gene discussed is CP; the disease is infection.