As shown in Table 2, ln(CA 125) was weakly correlated with 6MWD, WHO-FC, ln(NT-proBNP), echocardiographic parameters (LVED, RVED, and pericardial effusion), and haemodynamic parameters [SvO2, mRAP, CI and pulmonary vascular resistance (PVR)]. This evidence concerns the gene NPPB and pericardial effusion.