ANXA3 and neoplasm: In ANXA3 overexpressing gastric cancer cells and patient-derived tumor specimens, an enhanced degree of epithelial-mesenchymal transition (EMT) was observed, which was evidenced by western blot results indicating increased expressions of mesenchymal markers vimentin and ß-catenin, a decreased expression of epithelial marker E-cadherin, and increased expressions of EMT-related transcription factors fibronectin, Slug and Snail (Wang and Li, 2016).