- ECOG 0-1- Proven colorectal liver metastases- Primary tumor stage ≤ T4a- Time from primary to LT ≥6 months- No major vascular invasion- Metastases isolated to liver- Previous CT for ≥3 months with stability or regression of CRLMs- CEA values are stable or decreasing- BRAF wild-type. This evidence concerns the gene BRAF and neoplasm.