In the high-risk score group, various immune-related pathways were inhibited, including the allograft rejection, primary immunodeficiency, graft versus host disease, the intestinal immune network for IgA production, autoimmune thyroid disease, T-cell receptor signaling axis, and natural killer cell-mediated cytotoxicity pathways (Figures 6(a) and 6(b)). The gene discussed is TBXT; the disease is autoimmune thyroid disease.