NUSAP1 and hepatocellular carcinoma: Another study was a transcriptome analysis; by analyzing microarray datasets incorporating cirrhosis and HCC subjects from GEO database, the author found that NUSAP1 was one of the top 5 significant genes that were associated with onset, progression, and prognosis of HCC and exhibited higher expression in HCC compared with normal livers (Shan et al., 2019).