Although there was a trend towards an increased CD4+/CD8+ ratio in the morbidly obese patients as compared to lean controls (2.06 [1.63;2.99] in LC, 2.31 [1.84;3.20] in MetS- and 2.57 [1.94;3.60] in MetS+), this was not significantly different after correction for the covariates (P=0.518). Here, CD8A is linked to metabolic syndrome.