Moreover, we observed the same results as all GBM samples by analyzing MES glioblastoma alone, in which tumors with high HSPA7 expression exhibited significantly increased infiltration of immunosuppressive cell populations and regulators, such as macrophages, TAM BMDMs, neutrophils, Tregs, and immune checkpoints (Supplementary Figures S5A, B). The gene discussed is HSPA7; the disease is glioblastoma.