Similarly, resveratrol, a natural polyphenolic compound, has been shown to have antiseizure effects on epilepsy models, such as status epilepticus, when it was administered before the induction of seizures (86) attributed to its ability to suppress proinflammatory cytokines TNF-α, which was reported to be regulated by mTOR cascade (87). The gene discussed is TNF; the disease is epilepsy.