Overexpression of BCAT1 in mice accelerates tumor growth in hepatocellular carcinoma (Zheng et al., 2016), breast carcinoma (Siddiqui and Williams, 1989), endometrial cancer (Wang P. et al., 2018), and myeloid leukemia (Hattori et al., 2017), while suppression of BCAT1 reduces proliferation in glioblastoma (an aggressive cancer of the brain and spinal cord) (Tönjes et al., 2013). Here, BCAT1 is linked to hepatocellular carcinoma.