CD86 and psoriasis: Nguyen et al. evaluated the proportion of intermediate monocytes with CD86 expression in 43 patients with psoriasis and found that the upregulated expression of CD86 on the intermediate monocyte subset was positively correlated with clinical severity as measured by the psoriasis area and severity index (PASI) scores and serum beta defensin-2 (BD-2) levels (Nguyen et al., 2018).