GCG and Hypoglycemia: Normal physiological responses to hypoglycemia mainly comprise activation of the sympathetic nervous system, secretions of norepinephrine from the sympathetic postganglionic nerve terminals, epinephrine from the adrenal medulla, glucagon from the pancreas, cortisol from the adrenal cortex, and growth hormones from the pituitary gland (Diedrich et al., 2002; Rickels, 2019).