Second, although we have observed transplanted-hCPCs promoted angiogenic effect in MI rats after 42 days and speculated that the paracrine role of hCPCs may play a key role in revascularization in hCPC-transplanted MI heart, the deep mechanisms of the BK-promoted paracrine effect on hCPCs were not investigated in this study. Here, KNG1 is linked to myocardial infarction.