By the way, an upregulation of LIN28B was also observed in metastatic lymph node [42]; deleting LIN28B could attenuate oncogenicity of human gingival epithelial cell line (SG) and hypopharyngeal squamous cell carcinoma cell line (FaDu) [42], and both of which were OSCC cells. Here, LIN28B is linked to squamous cell carcinoma.