APC and colorectal carcinoma: To explore whether these truncated variants can be part of the recombinant DC and facilitate β-catenin recruitment and phosphorylation, we expressed and purified the DC in the context of APC mutant variants found in commonly used CRC cell lines (APC T1556∗ from COLO-205, APC Q1338∗ from SW480, and APC S811∗ from COLO-320DM; Figure 2A; Table S10).