We confirmed younger age, female gender, no history of prior CABG or smoking, no arterial hypertension, presence of COPD, no treatment with 3rd generation P2Y12, no direct transport to hospital, Killip class I or II, no history of diabetes and greater body mass at admission to be significant predictors of MINOCA among STEMI patients qualified for urgent coronary angiography. Here, P2RY12 is linked to chronic obstructive pulmonary disease.