We performed correlation analysis between IGSF10 and five MMR genes (MLH1, MSH2, MSH6, PMS2, and EPCAM) and observed negative correlation between IGSF10 and EPCAM in LUAD, and significant positive correlation between IGFS10 and MMRs in Cervical squamous cell carcinoma (CESE), pancreatic adenocarcinoma (PAAD), and head and neck squamous cell carcinoma (HNSC) (Figure 6B). Here, MLH1 is linked to head and neck squamous cell carcinoma.