KEGG pathway analysis indicated that RSPH14 targets were associated with the regulation AMPK signaling pathway, rheumatoid arthritis, collecting duct acid secretion, streptomycin biosynthesis, synaptic vesicle cycle, epithelial cell signaling in Helicobacter pylori infection, and mucin type O‐glycan biosynthesis (Fig. 6C). Here, MUC5AC is linked to rheumatoid arthritis.