De Silva De Silva SR SR Barnard Barnard AR AR Hughes Hughes S S Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy Proc Natl Acad Sci USA Proc Natl Acad Sci USA 2017 2017 114 114 11211 11211 11216 11216 10.1073/pnas.1701589114 10.1073/pnas.1701589114 28973921 28973921. The gene discussed is OPN4; the disease is retinal degeneration.