Synaptophysin expression was also relatively common in EWS (on average 23%) [34, 40, 45] and melanoma (on average 35%) [47, 50], while in SFT [19, 30, 33], chordoma [39], and the pancreatic SEMN [11], synaptophysin expression seems to be rare. The gene discussed is SYP; the disease is melanoma.