A previous study reported that overexpression of ARHGEF3 played a vital oncogenic role in nasopharyngeal carcinoma pathogenesis by preventing cell apoptosis through the overexpression of baculoviral IAP repeat containing 8, and ARHGEF3 might be used as a new prognosis biomarker and effective therapeutic target for human NPC [33]. The gene discussed is BIRC8; the disease is nasopharyngeal carcinoma.