The differentially expressed genes associated with ADORA2B were then evaluated for potential functional pathways using KEGG (ribosome, proteoglycans in cancer, fluid shear stress, and atherosclerosis, etc.), PANTHER (FAS, EGF receptor, apoptosis, etc.), and Reactome (influenza infection, major pathway of rRNA processing in the nucleolus and cytosol, cell cycle, etc.)pathway analyses (Figure 6B). This evidence concerns the gene ADORA2B and atherosclerosis.