We compared the percentages of peripheral blood CD33+CD4+CXCR5+CD45RA− Tfh-like, PD-1+ Tfh-like, CXCR3+CCR6− Tfh1-like, CXCR3−CCR6− Tfh2-like, CXCR3−CCR6+ Tfh17-like, and CXCR3+CCR6+ Tfh1/17-like cell subsets (based on the expression of CXCR3 and CCR6) in healthy controls and RA patients. The gene discussed is CD33; the disease is rheumatoid arthritis.