Gu et al. performed WGCNA based on the TCGA database and found two hub modules (turquoise module and blue module) and 13 hub genes (SNRPD2, PRR11, SKA3, etc.)that have a high correlation with progression and prognosis in HCC (Gu et al., 2020). This evidence concerns the gene SKA3 and hepatocellular carcinoma.