Apatinib (AiTan, China), also known as rivoceranib, is an oral small-molecule tyrosine kinase inhibitor (Tian et al., 2011) which highly selectively binds to vascular endothelial growth factor receptor 2 (VEGFR-2) and suppresses tumor angiogenesis (Jayson et al., 2016). Here, KDR is linked to neoplasm.