TP53 and metastatic neoplasm: TCGA data analyzed from metastatic tumor samples identified upregulated miRNA target genes to be involved in pathways in cancer, T cell receptor signaling pathway, cell cycle, p53 signaling pathway, B cell receptor signaling pathway, MAPK signaling pathway, JAK-STAT signaling pathway, ErbB signaling pathway, NOD-like receptor signaling pathway, and mRNA surveillance pathway (Figure 5).