KEGG analysis of the upregulated (Figure 3C; Supplementary Figure 4 and Supplementary Table 11) and downregulated (Figure 3D; Supplementary Figure 5 and Supplementary Table 12) miRNAs following PGRMC1 silencing identified enrichment to similar KEGG terms observed in the AG-205 treatment group, such as p53 signaling pathway, cell cycle and pathways in cancers. This evidence concerns the gene PGRMC1 and cancer.