It has been discovered that BRD9, PPP2R5A, and DVL2, are candidate genes for alternative splicing in SF3B1 K700-mutant chronic lymphocytic leukemia (114–116), while ABCC5, UQCC, and CRNDE are possible targets in three uveal melanoma cases mixed with R625 and K700 mutations (117). Here, SF3B1 is linked to B-cell chronic lymphocytic leukemia.