Indeed, this herbal medicine can ameliorate pulmonary lesions as it downregulates alveolitis and the Ashcroft score, the underlying mechanism for this might relate to the downregulation of MPO, α-SMA, HYP, collagen I, collagen III, and inflammatory factors (TNF-α, IL-1β, and IL-6). Here, ACTA1 is linked to hypersensitivity pneumonitis.