Bibenzyl of 4,5,4′-trihydroxy-3,3′-dimethoxybibenzyl (TDB) extracted from Dendrobium ellipsophyllum has gained interest due to its induction of apoptosis and repression of epithelial to mesenchymal transition (EMT) through Akt inhibition in human lung cancer cells [33]. This evidence concerns the gene AKT1 and lung cancer.