Bibenzyl of 4,5,4′-trihydroxy-3,3′-dimethoxybibenzyl (TDB) extracted from Dendrobium ellipsophyllum has gained interest due to its induction of apoptosis and repression of epithelial to mesenchymal transition (EMT) through Akt inhibition in human lung cancer cells [33]. The gene discussed is AKT1; the disease is lung carcinoma.