As shown in Supplementary Figures 10A–10G, the expression of PD-L1 (p=2e−11), CTLA4 (p=4.5e−8), HAVCR2 (p=1e−15), LAG3 (p=1.5e−9), PDCD1 (p=5.7e−7), PDCDG2 (p=2.22e−16), and TIGIT (p=7.6e−8) in BC tissues was significantly higher than that in normal tissues. This evidence concerns the gene HAVCR2 and breast cancer.