JAK2 and primary familial polycythemia due to EPO receptor mutation: Primary acquired erythrocytosis, i.e., somatic erythrocytosis (OMIM ID: 133100), is the consequence of somatic genetic variants in Janus kinase 2 (JAK2) gene and SH2B adaptor protein 3 (SH2B3) gene, which lead to constant activation of EPO signaling pathway (McMullin and Cario, 2016; Maslah et al., 2017; Bento, 2018).