The top pathways (count number ≥10) included African trypanosomiasis, the adipocytokine signaling pathway, NAFLD, insulin resistance, the FoxO signaling pathway, the AMPK signaling pathway, the PPAR signaling pathway, type II diabetes mellitus, the longevity regulating pathway, and the mTOR signaling pathway (Figure 4C and Supplementary Figure S1). The gene discussed is PPARA; the disease is metabolic dysfunction-associated steatotic liver disease.