GSK3B and cardiovascular disorder: In cardiovascular diseases, GSK-3β is involved in the regulation of cardiomyocyte proliferation (Kerkela et al., 2008), cardiac fibrosis (Lal et al., 2014), myocardial remodeling (Woulfe et al., 2010), and cardiomyocyte apoptosis (Kaga et al., 2006).