KDM1A and osteosarcoma: Using gene expression profiling and immunohistochemistry, the authors demonstrated that LSD1 may be overexpressed in several histologic subtypes of bone sarcoma and STS, including chondrosarcoma, Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, and synovial sarcoma, and this overexpression of LSD1 primarily showed nuclear localization [40].