Using gene expression profiling and immunohistochemistry, the authors demonstrated that LSD1 may be overexpressed in several histologic subtypes of bone sarcoma and STS, including chondrosarcoma, Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, and synovial sarcoma, and this overexpression of LSD1 primarily showed nuclear localization [40]. Here, KDM1A is linked to bone sarcoma.