MUC2 and colitis: The percentage of MUC2+ goblet cells was comparable in WT and Prkar2a−/− mice at the steady state, while during DSS-induced colitis, the number of MUC2+ goblet cells in Prkar2a−/− mice was higher than that in WT mice, suggesting a lower goblet cell loss in Prkar2a−/− mice during colon inflammation (Fig. 5a).