According to The Cancer Genome Atlas (TCGA) datasets, BCAT1 was up-regulated in pancreatic cancer samples with lymph node metastasis compared with those without lymph node metastasis (Fig. 2f) (p = 0.02, Student’s t-test), and BCAT1 expression was negatively associated with overall survival (Fig. 2g) (p = 0.028, log-rank test). This evidence concerns the gene BCAT1 and familial pancreatic carcinoma.