AKT1 and schizophrenia: The interaction of four single nucleotide polymorphism (SNP) loci, rs1130214 (AKT1), rs456998 (FCHSD1), rs7211818 (RAPTOR), and rs1053639 (DDIT4), was reported to predict the extrapyramidal response of patients with schizophrenia after using antipsychotic drugs.