To search for specific m6A readers in CCA cells, we again analyzed TCGA database and found that 6 m6A readers, including IGF2BP2, YTH domain containing 2 (YTHDC2), embryonic lethal, abnormal vision, and Drosophila-like protein 1 (ELAVL1), were highly expressed in CCA tumors, with IGF2BP2 displaying the highest expression (Supplementary Figure S5B). Here, YTHDC2 is linked to cholangiocarcinoma.