Moreover, Ephx2, Fam111a, Gng2, Gnb3, Gng8, Gnao1, Kcnj3, Kcnj6, and Kcnj9 may play critical roles in the pathogenesis of PD, providing a foundation for further studies into the molecular mechanisms of PD. The gene discussed is FAM111A; the disease is Parkinson disease.