TUNEL staining and Western blot analysis manifested that the apoptosis of ovarian GCs in rats was significantly increased after PCOS modelling, accompanied by increase in caspase‐3 and Bax levels and reduction in Bcl‐2 expression, and these trends were further promoted by ox‐HDL treatment (Figure 3A‐C). The gene discussed is BAX; the disease is polycystic ovary syndrome.