To test the possible transcriptional activation of these genes by PU.1 binding, we analyzed ChIP‐Seq data of PU.1 in THP‐1 cells differentiated with PMA (phorbol 12‐myristate 13‐acetate), representing a Mφ‐like cell model (GSE25426), and Ramos cells, a B cell line derived from Burkitt lymphoma (GSE139810).48, 49. The gene discussed is SPI1; the disease is Burkitt lymphoma.