In addition, Rap1b expression had significant correlation with infiltrating levels of B cells in 21 types of cancer, CD4 + T cells in 18 types of cancer, CD8 + T cells in 24 types of cancer, neutrophil in 27 types of cancer, macrophage in 26 types of cancer and dendritic in 26 types of cancer (Supplementary Figure 3). This evidence concerns the gene CD4 and cancer.