Moreover, to investigate whether EGR1 facilitated anticancer effect of Scutellarin on osteosarcoma cell through regulating LINC00857/miR‐150‐5p/c‐Myc axis, we first inhibited EGR1 in 143B cells with or without LINC00857 knockdown, and then, these cells were treated with or without 500 μM Scutellarin for 48 h. The gene discussed is LINC00857; the disease is osteosarcoma.