Several oncogenic lncRNAs such as PCAT-1, SNHG5, BCAR4, GHET1, HOTAIR, PVT1, MALAT1, UCA1 and NEAT1, as well as certain tumor suppressive lncRNAs, have been demonstrated to involve in MDR of GC (Table 1). This evidence concerns the gene PVT1 and gastric cancer.