These cottonseed extracts affect human cancer cell growth28 and regulate diacylglycerol acyltransferase (DGAT) and anti-inflammatory tristetraprolin (TTP/ZFP36) gene expression in mouse macrophages27,30, but has minimal effect on the expression of human antigen R (HuR), a protein stabilizing some cytokine mRNAs involved in tumorigenesis and inflammation45. Here, ZFP36 is linked to cancer.