AFF3 and cancer: Fusion partners of FGFR2 reported specifically in breast cancer are AFF3, CASP7 and CCDC6 [38, 39], while partners identified in other cancers include TACC and KIAA family members, PPHLN1, NTRK1, BICC1, AHCYL1, OFD1 and SLC45A3 [38, 40–42].