Our data highlighting effective targeting of oncogenic FGFR2 and FGFR4 alterations in specific PDX led us to analyze the METABRIC and TCGA datasets using cBioPortal to determine the frequency of FGFR2 and FGFR4 genomic and expression changes in different breast cancer subtypes (Fig. 5a, Additional file 4: Fig. S8a). The gene discussed is FGFR4; the disease is breast carcinoma.