In a study published in this issue of the Journal of Clinical Hypertension,1 Peri‐Okonny and coworkers investigated the effects of eplerenone, a selective mineralocorticoid receptor (MR) antagonist, and amlodipine, a dihydropyridine calcium channel blocker, on exercise pressor reflex in hypertensive patients. The gene discussed is NR3C2; the disease is Hypertension.